“Sustainable Water: The Keystone for Economy, Environment, Health and Security” In Southeast Asia, water resources are under strain due to rapid urbanization and industrialization. The situation is made worse by water-related disasters, climate change and poor governance in the region. Water resource issues include inadequate drinking-water supply and sanitation facilities, water pollution, floods, the siltation of river systems, and the management of rivers and large dams present special management challenges. Barriers to addressing these issues include poverty, illiteracy, rapid population growth, and ineffective institutions and policies for developing, distributing, pricing, and conserving water resources. The complex patterns of these issues are shaped by differences in wealth, environment, and political systems. The staging of the Global Water Conference 2016 in Yangon is meant to address the issues of water supply and resources management in the SEA region. This conference is designed to facilitate the implementation of the water management policies and encouraging collaboration between those working on water resources management and water technologies, and those working on environmental, public health, economic growth and other issues.