Host by Henan College Graduation Employment Promotion Association, support by Zhengzhou University, Henan University, Henan Polytechnic University, Henan University of Sciencce and Technology, North China University of Water Resources and Electric Power and Academic Exchange Information Center, the 2021 International Conference on algorithms, high performance computing and artificial intelligence (AHPCAI 2021) will be held in Sanya, China from November 19 to 21, 2021. The conference focused on the research fields of algorithms, high performance computing and artificial intelligence. The conference aims to provide a platform for experts, scholars, engineers and technicians engaged in the research of algorithms, high performance computing and artificial intelligence to share scientific research achievements and cutting-edge technologies, understand the trend of academic development, broaden research ideas, strengthen academic research and discussion, and promote the industrial cooperation of academic achievements. Experts, scholars, business people and other relevant personnel from universities and scientific research institutions at home and abroad are invited to attend the conference. Sincerely invite you to attend the conference!